Tweakment Finder TWEAKMENT



A quick guide to collagen-stimulating filler

By Georgia Seago
7th February 2023

Did you know that there’s more than one sort of dermal filler?

Hyaluronic acid (HA) fillers are the most common, and the type used in the most traditional ways – to enhance lips, replace volume underneath hollow eyes, straighten out a hooked or bumpy nose, or add definition to the jawline, for example. But there’s another type called stimulating fillers (usually referred to as ‘bio’ or ‘collagen-stimulating’), which open up further rejuvenating possibilities, but we’ll come onto that in a bit.

Within the HA fillers category there are different types that are best suited to these various concerns. The type of filler a good practitioner will inject will be dependent on the effects you’re after, and which part of the face you are hoping to have injected. Say it’s your lips – this is best done with a soft and fluid type of HA-based filler, which will give a soft and pliable result.

On the other end of the spectrum, the best type of filler for a non-surgical rhinoplasty or to contour the jaw – where the filler is sitting closer to the bone to give structure and lift – will be from a stiff, less yielding type of filler with a high ‘G-prime’, which means it will hold its shape more firmly for longer and give a crisp and definitive result. HA fillers tend to last for between six and 18 months, which again depends on where you have it injected and related factors that lead filler to degrade. So, if you want something longer-lasting that gives more bang for your buck – and providing your concern is suitable – it’s time to get acquainted with collagen or bio-stimulating fillers.

Enter, collagen-stimulating fillers

This breed of fillers, which tend to last for 18 months to four years, is made from substances such as poly-L-lactic acid or calcium hydroxyapatite, which have a sculpting effect and give some immediate volume to the face in the areas where they’re injected, but also have a secondary effect of stimulating collagen production in the surrounding area over time. This collagen will remain in the face after the filler itself has dispersed, which is great bonus if you’re concerned with signs of ageing. They’re also popular for making older hands look more youthful, with great success.

The longevity of stimulating fillers can also be a drawback, depending on how you look at it. Unlike HA fillers, stimulating fillers can’t be dissolved, so if you don’t like the results, you’re stuck with them until the filler eventually degrades naturally. So, if it’s your first foray into injectable fillers it might be advisable to begin with HA and, if you’re happy with how your face looks, speak to your practitioner about stimulating fillers for your next treatment.

But if you’re really wanting to look refreshed overall, with smoother, tighter skin and more restored structure to your face, this may well be the route to go down. It’s also worth noting that stimulating fillers are suited to those aged around 35 and up – if you’re younger it’s very likely you just won’t be showing the signs of ageing that warrant this kind of treatment – lucky you.

Which stimulating filler?

Your practitioner will have their own reasons behind their preferred product, but these are the ones currently available in the UK:

  • Sculptra is made from tiny particles of poly-L-lactic acid, a synthetic substance that has been safely used in medicine, in dissolvable sutures/stitches, since the 1980s. The poly-L-lactic acid takes around six months to be absorbed by the skin, by which time it has built new collagen that will last for two years.
  • Ellansé contains minute round particles of polycaprolactone (a bioabsorbable material that is also used in sutures for stitches) that slowly get absorbed by the body, but in the meantime are busy stimulating collagen growth.
  • Radiesse has particles of calcium hydroxylapatite (a bone-like substance that also eventually gets absorbed) which form a kind of miniature scaffold within the skin, around which a network of new collagen forms
  • And the latest to join the line-up, HArmonyCa, is a hybrid filler which is creating a lot of industry buzz. It’s the first of its kind and combines hyaluronic acid gel, which gives initial volume, with spheres of calcium hydroxyapatite to provide a long-term lift through collagen synthesis, and is said to be great for improving skin texture in areas including the lower face and the backs of the hands.




The Tweakments Guide Takeaway

Hyaluronic acid fillers and collagen-stimulating fillers work in different ways in the face. Make sure you find a great practitioner before treatment, so that they can advise you what's best for you.


Video Hub

Find a Practitioner


Practising for

0 years


3 miles


Didn't find what you were looking for?

Post a Question

Please enter your name, email address and question for Alice.

 Post Anonymously

Tick this box to hide your name on answers page. We will only print your initials.


By using this service you agree to our terms and conditions and privacy policy

Thank you for using The Tweakments Chatbot. We would like to know how was your experience with us today. Can you spare a minute to share your feedback?

Was the chatbot helpful in finding what you were looking for today?

Yes No

In few words could you please tell us why, so we can improve your experience in the future.

Would you use the chatbot next time you visit the website?

Yes No

In few words could you please tell us why, so we can improve your experience in the future.

Overall, how would you rate your experience using The Tweakments chatbot.

Thank you for your feedback.